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[Preprint]. 2023 Jun 15:2023.02.01.526652. [Version 4] doi: 10.1101/2023.02.01.526652

PMC9915647.2; 2023 Feb 6
PMC9915647.3; 2023 Apr 21
PMC9915647.4; 2023 Jun 15

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Figure 6. — (A) Boxplot showing luciferase reporter activities of different CRX variants. P-values for one-way ANOVA with Turkey honestly significant difference (HSD) test are indicated. p-value: ****: ≤0.0001, ***: ≤0.001, ns: >0.05. (B-D) Rhodopsin (RHO, green) immunostaining is absent in P3 WT retina but detected in Crx^E80A/+ and Crx^E80A/A retinas. Nuclei are visualized by DAPI staining (Blue). Arrow indicates the sporadic RHO staining in Crx^E80A/+ sample. ONBL: outer neuroblast layer; GCL: ganglion cell layer. Scale bar, 100μm.