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[Preprint]. 2023 Jan 31:2023.01.30.526383. [Version 1] doi: 10.1101/2023.01.30.526383

Fig. 4. The NTD of A3B is sufficient for A3B relocalization mediated by HCMV.

Fig. 4.

(A) Representative IF microscopy images of ARPE19 cells transiently expressing EGFP alone, A3B-FL-EGFP, A3B-NTD-EGFP, and A3B-CTD-EGFP, incubated with medium alone (mock) or infected with TB40-mCherry for 72 hrs (10 μm scale).

(B) Quantification of A3B-FL, A3B-NTD, and A3B-CTD subcellular localization phenotype shown in panel A. The dot-plot chart shows the ratio between nuclear and cytoplasmic fluorescence intensity (n>25 cells per condition; p-values were obtained using unpaired student’s t-tests).

(C) Representative IF microscopy images of HeLa cells transiently expressing EBV BORF2-FLAG together with EGFP alone, A3B-FL-EGFP, A3B-NTD-EGFP, and A3B-CTD-EGFP (10 μm scale).