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[Preprint]. 2023 Jun 22:2023.02.01.526470. Originally published 2023 Feb 2. [Version 2] doi: 10.1101/2023.02.01.526470

PMC9915672.1; 2023 Feb 2
PMC9915672.2; 2023 Jun 22
PMC9915672.4; 2024 Jul 6
PMC9915672.5; 2024 Sep 27

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FIGURE 3: — A. Rasters of the average fluorescence versus sound pressure level for all neurons imaged in the SST-Cre mice, calculated over the optimal time window for each cell and each sound and laser condition (see Methods). Rasters from left to right correspond to SST activation with no laser power, medium laser power and high laser power. The thick blue line at the bottom of each raster indicates the SST interneurons. Cells are ordered given their response at 90dB and no laser power. B. Average fluorescence over a 1-s fixed window as a function of sound pressure level for the whole population of SST neurons recorded (132 neurons), when the SST population is activated. C. Average fluorescence over a 1-s fixed window as a function of sound pressure level for the whole population of non-SST neurons recorded (2152 neurons), when the SST population is activated. D. Cumulative distribution function of sparseness for the population of non-SST neurons, when the SST population is activated. E. Average activity sparseness as a function of sound pressure level for each population of neurons (SST neurons excluded), when the SST population is activated. F. Rasters of the average fluorescence versus the sound pressure level for all neurons imaged in the VIP-Cre mice, calculated over the optimal time window for each cell and each sound and laser condition (see Methods). Rasters from left to right correspond to VIP activation with no laser power, medium laser power and high laser power. The thick green line at the bottom of each raster indicates the VIP interneurons. Cells are ordered given their response at 90dB and no laser power. G. Average fluorescence over a 1-s fixed window as a function of sound pressure level for the whole population of VIP neurons recorded (226 neurons), when the VIP population is activated. H. Average fluorescence over a 1-s fixed window as a function of sound pressure level for the whole population of non-VIP neurons recorded (3095 neurons), when the VIP population is activated. I. Cumulative distribution function of sparseness for the population of non-VIP neurons, when the VIP population is activated. J. Average activity sparseness as a function of sound pressure level for each population of neurons (VIP neurons excluded) when the VIP population is activated. For all panels, black, pink and red colors correspond to no laser power (0 mW/mm²), medium laser power (~0.3 mW/mm²) and high laser power (~3.5 mW/mm²), respectively (see Methods for power calibration).