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Transmission Electron Microscopy (TEM). Ciliary biopsies of patients with the RSPH4A (c.921+3_921+6del (intronic)) founder mutation. (a,b) Normal, healthy subject. (c,d) Abnormal central complex microtubule configuration, (9 + 3). (e,f) Abnormal peripheral and central microtubule organization and configuration, (9 + 4). Scale bar for (a,c,e): 50 nm. Illustrations (b,d,f) were created with BioRender.com (accessed on 24 November 2022).
