Table 2.
Number and percent of Deafness Variation Database missense variants belonging to each AlphaFold2 confidence range based on Deafness Variation Database classification.
| DVD Classification | <50 | 50–70 | 70–90 | >90 |
|---|---|---|---|---|
| B (1.4%) | 719 (0.6%) | 231 (0.2%) | 506 (0.4%) | 269 (0.2%) |
| LB (21.8%) | 15395 (12.0%) | 3153 (2.5%) | 5973 (4.7%) | 3386 (2.6%) |
| LP (2.1%) | 579 (0.5%) | 203 (0.2%) | 827 (0.7%) | 832 (0.7%) |
| P (4.9%) | 1201 (0.9%) | 470 (0.4%) | 2084 (1.6%) | 2573 (2.0%) |
| VUS (70.1%) | 25707 (20.1%) | 10306 (8.0%) | 30106 (23.5%) | 23647 (18.5%) |
| Total | 43611 (34.1%) | 14393 (11.3%) | 39574 (30.9%) | 30956 (24.0%) |