Table 3.

Average MolProbity refinement statistics for all deafness associated protein models in OtoProtein2 before and after optimization with Force Field X. A lower clash score, a lower percentage of poor rotamers, a higher percentage of favored backbone phi/psi angles, fewer backbone outliers and lower MolProbity score are each better.

Optimization	Clash Score	Poor Rotamers	Favored Backbones	Backbone Outliers	MolProbity Score
AlphaFold2	20.75	4.32%	76.21%	15.25%	2.86
OtoProtein2	0.11	1.12%	93.50%	1.05%	0.97