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[Preprint]. 2023 Feb 2:2023.01.31.23285242. [Version 1] doi: 10.1101/2023.01.31.23285242

Figure 2: Relationships between age and disease progression.

Figure 2:

The relationship between total TDP-43 pathology, age of disease onset, age at death and disease duration with total TDP-43 pathologic burden (as measured with SuStaIn stage) across all three diagnostic categories. SuStaIn stage was strongly related with total TDp-43 pathology across all diagnostic groups. LATE-NC showed a significant positive relationship between SuStaIn stage and age (at onset and at death), whereas FTLD-TDP showed a significant negative relationship with age and disease duration.