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. 2023 Feb 10;10(2):e00929. doi: 10.14309/crj.0000000000000929

Figure 1.

Figure 1.

(A) Skin lesion (arrow) on the right cheek with biopsies returning positive for Kaposi sarcoma. (B) Large ulcer (arrow) (>2-cm) deeply cratered ulcer noted in the sigmoid colon, biopsy-positive for Kaposi sarcoma. (C) Large (>2-cm) deeply cratered ulcer (arrow) noted in rectum, biopsy-positive for Kaposi sarcoma. (D) Low-power view shows an infiltrative spindle cell proliferation occupies the colonic mucosa suggestive of KS (H&E 40×, rectal ulcer biopsy). (E) Higher-power view shows the tumor cells with uniform spindled nuclei and extensive red blood cell extravasation, suggestive of KS (H&E 200×, rectal ulcer biopsy). (F) IHC stain for human herpesvirus-8 shows diffusely and strongly nuclear staining in the spindled tumor cells, suggestive of KS (IHC, 200×, rectal ulcer biopsy). H&E, hematoxylin and eosin; IHC, immunohistochemical; KS, Kaposi sarcoma.