Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jan 19;24(3):1991. doi: 10.3390/ijms24031991

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Conditioned medium with VAT tissue promotes cardiomyocytes’ gene expression alteration and hypertrophic/fibrotic signaling. qPCR experiments showed that fat stimulation from Obese rats promoted (a) IL-33 expression while it reduced (b) ST2L. (c) sST2 was not modified. Fat stimulation reduced (d) Epac1 expression. (e) The graph showed a negative—but not significant—correlation between ST2L and Epac1 expression. Fat stimulation reduced (f) YY1 expression in both Lean and Ob and (g) Mef2A expression in both Lean and Ob versus CTR. (h) The graph showed a positive correlation between YY1 and Epac1 while (i) a negative correlation emerged between ST2L and. Student’s t-test: * p < 0.05. Full square stands for Obese rats, while full circle stands for Lean rats.