Table 2.

Clinical characteristics of probands carrying likely pathogenic or pathogenic variants in desmoplakin (DSP) gene.

Patients	Sex	Age at Diagnosis (Years)	MAEs	Syncope	Chest PAIN	Palpitations	Presumed Myocarditis	NYHA Class	ICD	FH of SCD	FH of DCM/ACM
1	F	40	SVT	No	Yes	Yes	No	II	Yes	Yes	DCM
2	M	51	No	No	No	No	No	II	Yes	Yes	DCM
3	F	44	No	No	No	Yes	No	I	No	No	DCM, ACM
4	M	32	No	No	No	No	No	I	No	No	DCM
5	M	31	No	Yes	No	Yes	Yes	I	Yes	Yes	No
6	F	57	No	No	Yes	Yes	No	II	No	No	No
7	M	32	No	No	Yes	No	Yes	I	No	No	No
8	M	31	No	No	No	No	Yes	II	Yes	No	No
9	F	18	No	No	Yes	Yes	Yes	I	No	No	No
10	M	25	No	No	Yes	Yes	Yes	I	No	Yes	No
11	F	46	No	No	No	Yes	No	II	Yes	Yes	Yes
12	F	43	No	No	No	Yes	No	I	No	Yes	DCM
13	M	41	No	Yes	No	Yes	No	I	Yes	Yes	ACM
14	F	42	No	No	No	Yes	No	II	Yes	Yes	No
15	F	64	No	No	Yes	Yes	Yes	II	Yes	No	DCM
16	F	46	SVT	No	Yes	Yes	No	I	Yes	No	No
17	M	20	No	No	No	Yes	No	I	Yes	No	ACM
18	M	68	No	No	Yes	Yes	Yes	I	Yes	Yes	No

MAEs: Major Arrhythmic Events; SVT: Sustained Ventricular Tachycardia; NYHA: New York Heart Association; ICD: Implantable cardioverter defibrillator; SCD: Sudden Cardiac Death; FH: Family history; DCM: Dilated Cardiomyopathy; ACM: Arrhythmogenic Cardiomyopathy.