Fig 4. Clear native PAGE analysis of the RBBP6-p53BD.

Clear native PAGE analysis of purified RBBP6-p53BD. (A): Tris-HCl buffer, with pH 8.3. Lane 1 is the RBBP6-p53BD in 50 mM sodium phosphate, pH 7. Lane 2 is the RBBP6-p53BD in 50 mM sodium phosphate, pH 7 after being heated to and cooled from 90°C to 20°C, as described in section 2.8. Lane 3 is the RBBP6-p53BD in 50 mM sodium phosphate, pH 7 with 2 M urea. (B): Imidazole-HEPES buffer, pH7.4. Lane 1 is the RBBP6-p53BD in 50 mM sodium phosphate, pH 7, and Lane 2 is the RBBP6-p53BD in 50 mM sodium phosphate, pH 7 after being heated to and cooled from 90°C to 20°C, as described in section 2.8. Protein samples were not equalised before loading onto the gels.