Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Left panel: AUCs obtained by hiPRS and a benchmark model during cross-validation (four folds). Average AUCs are 0.72 and 0.57 respectively for hiPRS and the benchmark model. Right panel: interactions selected by hiPRS, and corresponding effect-sizes, when fitting the model on the whole dataset. In grey are reported the pathways each SNP belongs to (cf. Materials and methods).
