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. 2023 Jan 24;24(3):2313. doi: 10.3390/ijms24032313

Table 2.

Future research topics proposed to improve NAFLD diagnosis and treatment.

Future Research Items to Be Addressed
  • 1.

    Discover new molecular pathways involved in NAFL development and in its progression to NASH.

  • 2.

    Clarify the role of each immune player involved in NAFLD and characterize their phenotype.

  • 3.

    Develop novel noninvasive techniques to diagnose and stratify NAFLD correctly.

  • 4.

    Collect and analyze longitudinal data to better understand the cellular and molecular changes in NAFLD progression.

  • 5.

    Identify new biomarkers for NAFLD prediction, diagnosis, stratification or disease reversion.

  • 6.

    Study novel therapeutic targets to prevent, halt or revert NAFLD.

  • 7.

    Develop new NAFLD animal models that fully simulate human pathology.