Table 3.
The uptake of 1-Me,Me and 1-Oct,Me in cancer cells. Cells were incubated with either 1-Me,Me or 1-Oct,Me, with each one tested at its IC50 value (9.8 μM 1-Me,Me on SVT2 and 2.3 μM 1-Oct,Me on A431). After 48 h, cells were analysed by ICP analysis, as described in the Materials and Methods section. Data shown are the means ± S.E. of three independent experiments.
| Samples | Pt ng/106 cells |
|---|---|
| Untreated SVT2 | <0.0001 |
| SVT2 incubated with 1-Me,Me | 0.772 ± 0.010 |
| Untreated A431 | <0.0001 |
| A431 incubated with 1-Oct,Me | 14.3 ± 1.3 |