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. 2023 Feb 1;24(3):2742. doi: 10.3390/ijms24032742

Figure 3.

Figure 3

S. sonnei and S. flexneri GMMA compared in wild type and T cell-deficient mice. S. sonnei LPS-specific (a) and S. flexneri 2a OAg-specific (b) total IgG (EU/mL) after prime and boost in wild type (WT) and T cell-deficient mice (Crl:CD1-Foxn1nu) immunized subcutaneously at day 0 and 28 with 0.5 µg (quantified as total OAg) of GMMA. Bactericidal titers against S. sonnei (c) and S. flexneri 2a (d) after boost expressed as IC50. Geometric mean (bar) is reported for all groups together with individual values (dots) and 95% confidence intervals (CI). * p < 0.05; ** p < 0.01; *** p < 0.001, Mann–Whitney test.