Table 1.
GMMA used in the study. The table summarizes all GMMA main characteristics and relative GMMA producer bacterial strains. n.d.: not determined.
| Antigen | GMMA Producing Strain | OAg Concentration (µg/mL) |
Protein Concentration (µg/mL) |
OAg/Protein Ratio |
|---|---|---|---|---|
| S. sonnei OAg+ GMMA | S. sonnei virG::nadAB, tolR::aph msbB1::erm msbB2::cat | 537.4 | 1858.9 | 0.29 |
| S. flexneri 1b OAg+ GMMA | S. flexneri 1b ΔtolR::frt msbB1a::frt msbB1b::frt | 2179.4 | 2264.9 | 0.96 |
| S. flexneri 1b OAg− GMMA | S. flexneri 1b ΔtolR::frt msbB1a::frt msbB1b::frt rfbG::erm | 0 (no OAg detected) | 1339.3 | n.d. |
| S. flexneri 2a OAg+ GMMA | S. flexneri 2a ΔtolR::aph msbB::cat | 1400.9 | 1794.6 | 0.78 |
| S. flexneri 2a OAg− GMMA | S. flexneri 2a ΔtolR::aph msbB::cat rfbG::erm | 0 (no OAg detected) | 1814.6 | n.d. |
| S. flexneri 3a OAg+ GMMA | S. flexneri 3a tolR::aph msbB::cat | 1961.1 | 1820.6 | 1.07 |
| S. flexneri 3a OAg− GMMA | S. flexneri 3a tolR::aph msbB::cat rfbG::erm | 0 (no OAg detected) | 784.5 | n.d. |