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. 2023 Jan 19;24(3):1980. doi: 10.3390/ijms24031980

Figure 5.

Figure 5

The most studied oncosuppressors and their target genes. MiR-145 has 3 target genes: neuroblastoma RAS viral oncogene homolog (N-RAS), MUC1, and vascular endothelial growth factors (VEGF). Let-7 family target genes: radixin (RDX), Harvey rat sarcoma viral oncogene homolog (H-RAS), high-mobility group AT-hook 2 (HGMA2), serine/threonine-protein kinase (PAK1), diaphanous-related formin 2 (DIAPH2), and integrin subunit beta (ITGB). MiR-205 and miR-200 have 2 mutual target genes: zinc finger E-box binding homeobox 1 and 2 (ZEB1, ZEB2).