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. 2023 Feb 1;24(3):2727. doi: 10.3390/ijms24032727

Figure 1.

Figure 1

Microglial cells in the outer plexiform layer (OPL). (A,B): retinal whole-mounts labeled with anti-Iba-1 at 20× magnification. Arrows indicate Iba-1+ microglial cells with retraction of the processes in the Dravet syndrome (DS) animals. (C,D): number of Iba-1+ microglial cells per retinal area 0.1502 mm2 by total retina and area € and by zone (D). (E,F): Arbor area of Iba-1+ microglia by total retina and area (E) and by zone (F). (G,H): Iba-1+ cell area by total retina and area (G) and by zone (H). Two-way ANOVA. Data expressed as mean value (±SD). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. Number of retinas used in the experiment: WT animals n = 6, DS animals n = 6. Sup: superior; Inf: inferior; Nas: nasal; Temp: temporal.