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. 2023 Jan 20;24(3):2037. doi: 10.3390/ijms24032037

Figure 2.

Figure 2

SiNPs induced apoptosis in MDA-MB-231 and ZR-75-1 cell lines. The influence of 5–15 nm SiNPs (100 µg/mL) on apoptosis (A–C) and necrosis (A,C,D) of both breast cancer cell lines, after 48 h. These cells were stained with Annexin V-FITC and PI. Representative dot plots for Annexin V-FITC and PI staining are shown in (A,C). Mean values from three independent experiments ± SD are presented. Significant alterations are expressed relative to adequate controls and marked with asterisks. Statistical significance was considered if * p < 0.001.