Table 4.
Differences in ratios indicating lipid content of HDL particles between HV and MS patients.
| Variable | All (N = 130) |
HV (N = 65) |
MS (N = 65) |
p |
|---|---|---|---|---|
| HDL-C / HDL-apoA-I | 0.37 (0.35, 0.40) | 0.39 (0.36, 0.41) | 0.36 (0.33, 0.38) | <0.001 |
| HDL1-C / HDL1-apoA-I | 0.65 (0.60, 0.71) | 0.64 (0.60, 0.69) | 0.65 (0.60, 0.72) | 0.869 |
| HDL2-C / HDL2-apoA-I | 0.48 (0.45, 0.51) | 0.49 (0.45, 0.53) | 0.47 (0.43, 0.50) | 0.011 |
| HDL3-C / HDL3-apoA-I | 0.39 (0.37, 0.40) | 0.40 (0.38, 0.41) | 0.38 (0.36, 0.39) | <0.001 |
| HDL4-C / HDL4-apoA-I | 0.26 (0.24, 0.27) | 0.26 (0.25, 0.28) | 0.24 (0.23, 0.26) | <0.001 |
| HDL-TG / HDL-apoA-I | 0.06 (0.06, 0.08) | 0.06 (0.05, 0.07) | 0.08 (0.06, 0.10) | <0.001 |
| HDL1-TG / HDL1-apoA-I | 0.12 (0.09, 0.17) | 0.11 (0.08, 0.13) | 0.15 (0.11, 0.19) | <0.001 |
| HDL2-TG / HDL2-apoA-I | 0.10 (0.08, 0.13) | 0.08 (0.07, 0.11) | 0.12 (0.09, 0.16) | <0.001 |
| HDL3-TG / HDL3-apoA-I | 0.08 (0.06, 0.10) | 0.07 (0.06, 0.08) | 0.09 (0.07, 0.12) | <0.001 |
| HDL4-TG / HDL4-apoA-I | 0.04 (0.04, 0.05) | 0.04 (0.03, 0.05) | 0.05 (0.04, 0.06) | <0.001 |
| HDL-PL / HDL-apoA-I | 0.52 (0.49, 0.54) | 0.53 (0.50, 0.55) | 0.51 (0.47, 0.54) | 0.002 |
| HDL1-PL / HDL1-apoA-I | 0.78 (0.74, 0.83) | 0.76 (0.73, 0.82) | 0.78 (0.74, 0.83) | 0.460 |
| HDL2-PL / HDL2-apoA-I | 0.74 (0.68, 0.78) | 0.73 (0.68, 0.79) | 0.74 (0.68, 0.76) | 0.694 |
| HDL3-PL / HDL3-apoA-I | 0.61 (0.60, 0.63) | 0.62 (0.60, 0.63) | 0.61 (0.59, 0.63) | 0.145 |
| HDL4-PL / HDL4-apoA-I | 0.36 (0.34, 0.37) | 0.36 (0.35, 0.37) | 0.35 (0.33, 0.37) | 0.001 |
Data are presented as median (q1, q3). Differences between HV and MS patients were tested with the Mann–Whitney U test. p-values < 0.05 are considered statistically significant and are depicted in bold. ApoA-I, apolipoprotein A-I; C, cholesterol; HV, healthy volunteer; HDL, high-density lipoprotein; MS, metabolic syndrome patient; N, number; PL, phospholipid; TG, triglyceride.