Table 2.

Prediction of Lipinski’s rule of five (updated) parameters by the SwissADME and pkCSM platforms.

Property	2	4	8	11
H-bond donors (<5)	0	1	0	1
H-bond acceptors (<10)	1	2	3	3
Mol. weight (160 to 480)	150	168	210	198
Log P (−0.4 to +5.6) 1	2.49	1.68	2.25	1.31
Log P (−0.4 to +5.6) 2	2.43	1.57	2.08	1.35
Heavy atoms (20 to 70)	11	12	15	14
Molar refractivity (40 to 130) 2	47	49	59	55
Surface area 1	68	73	90	85

¹ From pkCSM; ² From SwissADME.