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. 2023 Jan 26;24(3):2411. doi: 10.3390/ijms24032411

Figure 5.

Figure 5

Effect of 48-h incubation of cortical astrocytes with various concentrations of sorafenib (So), selenium nanoparticles (SeNPs), and selenium-sorafenib nanocomplex (SeSo). (A–C)–Cytograms demonstrating the viability of astrocytes after 48-h pre-incubation with different concentrations of So (A), SeNPs (B), and SeSo (C). X-axis: the intensity of PI fluorescence; Y-axis: the intensity of Hoechst 33342 fluorescence. Cells were stained with the probes after 24-h incubation with different concentrations of compounds. (D–F) Comparison of the effect of different concentrations of So, SeNPs, and SeSo on survival of astrocytes after 48-h pre-incubation. Panels (D–F) is a calculation (technical replicate) of the data (mean ± SE) presented in panels (A–C), performed in three repetitions, n = 3. Cell images are shown in Supplementary Figures S10–S12.