Figure 4.

Effect of stilbenoid monomers and dimers on LPS-induced ROS formation in bmDCs. Murine bmDCs were administered carboxy-H₂DCFDA and incubated in the absence or in the presence of the given stilbenoids (30 µM) for 30 min before stimulation with LPS (100 ng/mL). After 4 h, ROS formation in bmDCs was determined by using flow cytometry to quantitate formation of oxidized carboxy-H₂DCFDA. The mean fluorescence index (MFI) is shown in panels (A) (monomers) and (B) (dimers). The original flow cytometry results for monomers and dimers are grouped in (C,D), respectively. *** p ≤ 0.001, **** p ≤ 0.0001.