Table 4.
Haplotype distribution of LGALS9 SNPs between ccRCC patients and controls.
| Haplotype * | ccRCC (%) | Control (%) | Odds Ratio [95% CI] | p-Value |
|---|---|---|---|---|
| A A C G | 120.88 (25.8) | 168.59 (20.7) | 1.335 [1.021~1.746] | 0.034 |
| A A C T | 0.00 (0) | 11.03 (1.4) | - | 0.011 |
| G A C G | 11.02 (2.4) | 9.88 (1.2) | 1.964 [0.826~4.672] | 0.120 |
| G A T T | 1.05 (0.2) | 13.43 (1.6) | 0.134 [0.018~0.980] | 0.020 |
| G G C G | 11.86 (2.5) | 20.90 (2.6) | 0.987 [0.480~2.032] | 0.972 |
| G G C T | 40.24 (8.6) | 67.47 (8.3) | 1.041 [0.692~1.567] | 0.846 |
| G G T G | 14.24 (3.0) | 28.41 (3.5) | 0.868 [0.455~1.658] | 0.668 |
| G G T T | 262.59 (56.1) | 483.95 (59.3) | 0.870 [0.690~1.098] | 0.241 |
| Global χ2 = 18.30, df = 7, p = 0.011 | ||||
* rs3751093, rs361497, rs4239242, and rs4794976. Significant results are bolded.