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. 2023 Jan 30;24(3):2627. doi: 10.3390/ijms24032627

Table 2.

Anti-metabolic syndrome and anti-inflammatory effects of grape phytochemicals.

Grape Phytochemicals Effects Subjects Ref
Wine Health-improving effects of wine Human [74]
Resveratrol Maintaining health condition
in high calorie intake
Mouse/
D. melanogaster/
C. elegans/
S. cerevisiae
[75]
Reducing risks of NAFLD and gut dysbiosis Mouse [76]
Atherosclerosis prevention Human [83]
Red wine polyphenol Atherosclerosis prevention,
effects in vascular smooth muscle cells
Human and
Bovine
endothelial cells
[77]
Red wine bioactive compound Anti-oxidative, thrombin inhibition,
lipase inhibition
Cells/Activity screening kit [78]
Flavonoids Anti-oxidative, anti-inflammatory,
anti-carcinogenesis,
circulatory system disease prevention
Human [79]
Alleviating collagen-induced arthritis Mouse [84]
Anti-ageing Human [85]
Grape phytochemicals, GSE,
K-FGF
Alleviating intestine related disordered Human/
Rat/Mouse
[80]
Grape seed extract (GSE) Lung fibrosis prevention Mouse [81]
Grape seed flan-3-ols Analysis of biosynthetic pathways
in nutraceuticals
Physical analysis [82]
Procyanidin Preventing senescence Mouse/
Human cells
[86]