AE |
adverse effect |
ACE |
angiotensin-converting enzyme |
AKT |
protein kinase B |
ARB |
angiotensin receptor blocker |
AXL |
tyrosine-protein kinase receptor UFO |
BAA |
beta-adrenoceptor antagonist |
BAD |
BCL2 associated agonist of cell death |
BP |
blood pressure |
CCB |
calcium channel blocker |
CVD |
cardiovascular disease |
CO |
cardiac output |
EFGR |
epidermal growth factor receptor |
ERK |
extracellular regulated kinase |
ET-1 |
endothelin-1 |
FDA |
food and drug administration |
FLT-3 |
fms-like tyrosine kinase 3 |
GF |
growth factor |
HGF |
hepatocyte growth factor |
HR |
hazard ration |
KIT |
tyrosine-protein kinase KIT or CD117 |
MAP |
mean arterial pressure |
MAPK |
mitogen-activated protein kinase |
MDM2 |
mouse double minute 2 |
MEK |
mitogen-activated protein kinase kinase-1 |
MET |
mesenchymal-epithelial transition |
MET |
tyrosine-protein kinase Met or hepatocyte growth factor receptor |
TKI |
multi-kinase inhibitor |
MTC |
medullary thyroid cancer |
mTOR |
mammalian target of rapamycin |
NO |
nitric oxide |
NTRK-2 |
neurotrophic tyrosine receptor kinase 2 |
OS |
overall survival |
PDGF |
platelet-derived growth factor |
PGI2 |
prostaglandins |
PI3K |
phosphoinositide 3 kinases |
PFS |
progression-free survival |
RAF |
rapidly accelerated fibrosarcoma |
RAS |
rat sarcoma |
RECIST |
Response Evaluation Criteria in Solid Tumors |
RET |
rearranged during transfection |
RTK |
receptor tyrosine kinase |
TC |
thyroid cancer |
TIE-2 |
angiopoietin-1 receptor |
TRKB |
tropomyosin receptor kinase B |
TRP |
total peripheral resistance |
VEGF |
vascular endothelial growth factor |
VEGFR |
vascular endothelial growth factor receptor |
VS |
versus |