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. 2023 Jan 31;19(1):e1010863. doi: 10.1371/journal.pcbi.1010863

Fig 1. Overview of maxATAC.

Fig 1

(A) maxATAC deep neural network models use DNA sequence and ATAC-seq signal to predict TFBS in new cell types. (B) The maxATAC training data per TF and cell type with OMNI-ATAC-seq (top: 74 "benchmarkable" TF models with ≥ 3 cell types available, bottom: 53 TF models with only 2 cell types for training). Teal boxes indicate ChIP-seq from ENCODE, while red boxes indicate data from GEO. Red stars denote cell types for which we generated OMNI-ATAC-seq. (C) Example applications of maxATAC TFBS prediction to primary cells, scATAC-seq and clinical studies combining DNA sequencing with ATAC-seq. Human image was created with BioRender.com.