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. 2023 Jan 23;24(3):2227. doi: 10.3390/ijms24032227

Figure 3.

Figure 3

An overview of the most prominent mechanisms of action and impact of metformin on different metabolic diseases in conditions of metabolic syndrome. AMPK: AMP-activated protein kinase, cAMP: cyclic adenosine monophosphate, FGF21: fibroblast growth factor 21, GLP-1R: glucagon-like peptide 1 receptor, LDL: low-density lipoprotein.