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. 2023 Feb 1;24(3):2787. doi: 10.3390/ijms24032787

Figure 1.

Figure 1

PEDF reduces myocardial infarct size and vascular leakage in AMI rats. (A) Representative images of the Evans Blue/TTC staining in myocardial tissues. (B) Quantification of myocardial infarct size. (C) Quantification of serum cTn-I concentration in rats. (D,E) Western blotting to detect the effect of PEDF on the expression of ZO-1. (F,G) Immunofluorescence to observe the effect of PEDF on vascular leakage; 15–20 images from each group were used for fluorescence intensity analysis. White arrows point to leakages; Scale Bar = 100 μm. Data are expressed as mean ± SD; n = 4; NS, no significant difference; * p < 0.05; ** p < 0.01.