Table 2.
Comparison of demographic data, oxidative stress, and embryo quality between Pre-MT and MT groups, and clinical outcomes.
| Pre-MT Group | MT Group | p Value | |
|---|---|---|---|
| Number of patients | 33 | 33 | |
| Age | 34.6 ± 3.7 | 36.4 ± 3.9 | n.s. |
| Body mass index (BMI) | 21.1 ± 3.2 | 21.2 ± 3.3 | n.s. |
| Anti-Müllerian hormone (AMH) (ng/mL) | 4.2 ± 4.8 | 1.8 ± 1.5 | n.s. |
| Diacron-Reactive Oxygen Metabolites tests (d-ROM) (CARR U) | 354.9 ± 66.1 | 321.1 ± 81.5 | n.s. |
| Biological Antioxidant Potential (BAP) (μmol/L) | 2222.5 ± 54.9 | 2270.3 ± 207.6 | n.s. |
| Total oocyte No. | 718 | 387 | |
| Average oocyte No. retrieved per patient | 8.4 ± 4.4 | 11.4 ± 6.9 | p < 0.05 |
| Total fertilized oocytes No. | 459 | 208 | |
| Average No. of fertilized oocytes per patient | 5.2 ± 3.1 | 6.2 ± 3.5 | p < 0.05 |
| Average fertilization rate (%) | 61.8 ± 19.9 | 59.3 ± 22.8 | n.s. |
| Total No. of transferable embryos | 163 | 119 | |
| Average transferable embryo rate per zygote (%) | 33.2 ± 23.2 | 62.4 ± 22.3 | p < 0.05 |
| Average good-quality embryo rate per zygote (%) | 6.9 ± 9.3 | 23.7 ± 24.4 | p < 0.05 |
| Average EQS of the transferable embryo on Day 3 | 1.1± 1.0 | 1.9 ± 0.9 | p < 0.05 |
| No. of embryos transferred | 98 | 78 | |
| No. of embryo transfers | 91 | 51 | |
| Clinical pregnancy rate per embryo transfer (%) | 0 | 27.4 (14/51) | p < 0.05 |
| Live birth rate per embryo transfer (%) | 0 | 21.5 (11/51) | p < 0.05 |
| No. of babies born | 0 | 13 | |
| Miscarriage rate (%) | ND | 21.4 (3 /14) |
There were no significant differences in demographic data and oxidative status between the Pre-MT and MT groups. The d-Rom value can be broken down as follows: {Pre-MT < 340 (CARR U) (57.1%), 341–400 (19%), 401–500 (19%), 500 (4.7%)}, {MT < 340 (CARR U) (69.5%), 341–400 (17.4%), 401–500 (8%), 500 (4.3%)}. The good-quality embryo rates, transferable embryo rates per zygote, and EQS significantly increased. The clinical pregnancy rates and live birth rates were improved after MT. EQS: Embryo Quality Scoring. p < 0.05 statistically significant.