Table 4.
Association between HDP-twin pregnancies with or without GDM and neonatal outcomes in twin pregnancies.
| Variables | HDP and GDM β/OR (95% CI) * |
p-Value | HDP and No-GDM β/OR (95% CI) * |
p-Value |
|---|---|---|---|---|
| MC twin pregnancies | ||||
| Gestational age at delivery | 1.06 (0.43, 1.69) | 0.001 | −0.59 (−1.20, 0.02) | 0.057 |
| Preterm birth | 0.44 (0.20, 0.97) | 0.042 | 2.15 (0.98, 4.71) | 0.055 |
| Birth weight | 174.90 (8.91, 340.89) | 0.039 | −61.36 (−217.69, 94.98) | 0.441 |
| LGA | 0.73 (0.16, 3.39) | 0.687 | 1.76 (0.56, 5.47) | 0.332 |
| SGA | 1.22 (0.42, 3.50) | 0.715 | 1.14 (0.51, 2.53) | 0.754 |
| Intertwin weight discordance | −0.02 (−0.05, 0.02) | 0.438 | 0.03 (−0.01, 0.06) | 0.105 |
| Discordant twins | 0.57 (0.22, 1.47) | 0.245 | 1.45 (0.78, 2.69) | 0.239 |
| DC twin pregnancies | ||||
| Gestational age at delivery | −0.10 (−0.59, 0.39) | 0.680 | −0.39 (−0.80, 0.03) | 0.066 |
| Preterm birth | 1.64 (0.93, 2.87) | 0.085 | 1.32 (0.87, 2.01) | 0.194 |
| Birth weight | −90.64 (−213.86, 32.58) | 0.149 | −156.97 (−257.92, −56.02) | 0.002 |
| LGA | 1.08 (0.47, 2.47) | 0.864 | 0.55 (0.23, 1.29) | 0.169 |
| SGA | 2.43 (0.93, 6.36) | 0.070 | 2.03 (1.02, 4.03) | 0.044 |
| Intertwin weight discordance | 0.02 (−0.00, 0.04) | 0.082 | 0.04 (0.02, 0.06) | 0.000 |
| Discordant twins | 3.37 (1.75, 6.49) | 0.000 | 2.83 (1.78, 4.48) | 0.000 |
DC: dichorionic, MC: monochorionic, GDM: gestational diabetes mellitus, HDP: hypertension disorders of pregnancy, LGA: large for gestational age, SGA: small for gestational age, OR: odds ratio, CI: confidence interval. * Adjustment for maternal age, prepregnancy BMI, nulliparity and mode of conception.