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. 2023 Feb 3;24(3):3028. doi: 10.3390/ijms24033028

Figure 1.

Figure 1

Cisplatin inhibits TFEB expression in mice kidney tissues and HK-2 cells. (A,B) Western blot assay and quantitative analysis of TFEB protein in kidney tissues of cisplatin-treated mice (intraperitoneal injection of cisplatin 0, 25, and 30 mg/kg). (C,D) Western blot assay and quantification of TFEB levels in HK-2 cells after exposure to increasing concentrations (0, 10, 20, 40, and 80 μM) of cisplatin for 24 h. Bars represent the mean ± SEM for at least three independent experiments. Cis: cisplatin. ** p < 0.01, *** p < 0.001, NS, non significant.