Skip to main content
. 2023 Feb 3;24(3):3028. doi: 10.3390/ijms24033028

Figure 3.

Figure 3

TFEB overexpression alleviates cisplatin-induced damage of HK-2 cells. (A) Western blot assay of TFEB expression in HK-2 cells infected with or without TFEB lentivirus. (B) After infection with lentivirus with or without TFEB, HK-2 cells were exposed to cisplatin (20 μM) for 24 h. The CCK-8 assay was used to detect cell viability. (C,D) Flow cytometry and quantitative analysis of apoptosis in HK-2 cells. (E,F) Immunoblotting analysis and quantitative data for PARP protein in HK-2 cells. Each bar represents mean ± SEM of at least three independent experiments. OE-TFEB: overexpressing TFEB; Cis: cisplatin. * p < 0.05, ** p < 0.01, *** p < 0.001, NS, non significant.