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. 2023 Feb 3;24(3):3047. doi: 10.3390/ijms24033047

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Knockdown FKBP5 enhanced the radiosensitivity of NPC cells by inhibiting autophagy: (A,B) RT-qPCR (A) and Western blot (B) assay of the expression of FKBP5 in CNE2R and CNE2 cells transfected with siFKBP5; (C) colony formation assay was performed to evaluate the influence of siFKBP5 on the survival fractions of CNE2R and CNE2 cells after irradiation; (D) fluorescence images of CNE2R cells transfected with siFKBP5 and mRFP-GFP-LC3-tagged adenovirus (×40); (E) Western blot assay of LC3 proteins in CNE2R cells after transfection with siFKBP5. * p < 0.05 compared with corresponding siNC or between indicated groups.