Table 1.
Downregulated genes with reduced 5hmC levels in TET2 knockdown cells.
| Downregulated genes with reduced 5hmC peaks in Exon regions in TET2 KD cells | |||||||||
| MYEOV | BEST1 | COLCA1 | CREBBP | KRT34 | FIBCD1 | TNNI2 | PLPP2 | TLCD1 | PLCB3 |
| TMC5 | TIMM44 | SLC4A2 | FAM107A | CARD10 | PDXP | MIB2 | TET3 | SNX8 | TNFSF14 |
| TEAD4 | NFATC4 | KRT23 | FASN | CFD | SEMA3B | LSP1 | ATAD3C | CCDC88B | CAPS |
| COX4I2 | MED24 | ATP2A1 | TNK2 | ENO1 | WNK2 | MIDN | IFI27 | TXNRD2 | EMILIN2 |
| CAPN12 | PLEKHB1 | DOCK6 | MUC4 | UPP1 | P4HTM | SERPINF1 | PTPRH | MSI1 | NDUFA4L2 |
| ZNF768 | ATG16L2 | MAL | B4GALT5 | SPTBN2 | KLF16 | SLC9A1 | LEFTY1 | MB | C15orf39 |
| KLK13 | EPHB6 | WTIP | TMEM205 | DOT1L | QRICH2 | ISYNA1 | CHD1 | HGD | RASGRP2 |
| HES6 | TNFSF13 | MKNK2 | REC8 | MYLPF | FBXL19 | REEP6 | RNF223 | MLPH | CCK |
| TBC1D1 | LTC4S | SIGIRR | ZNF652 | FUT4 | PALM | H19 | ARRB2 | MSI2 | TF |
| SLC7A1 | ABCA7 | ||||||||
| Downregulated genes with reduced 5hmC peaks in Intron regions in TET2 KD cells | |||||||||
| ATP6V1B1 | AGAP1 | INF2 | PALM | B4GALT5 | NCMAP | ADIPOR2 | MLPH | PPARGC1B | WNK2 |
| KCNQ1 | PPP1R9B | CARD10 | DOT1L | SLC6A17 | BFSP2-AS1 | ABCA7 | REEP6 | SSBP3 | SMDT1 |
| CORO2A | SIGIRR | TEAD4 | NTF3 | MSI2 | CCDC57 | TNK2 | SLC4A2 | BGN | PRKCB |
| LYPD5 | MUC4 | SNX8 | FAM20A | LMTK3 | TXNRD2 | TJP3 | CSK | PHLPP1 | JDP2 |
| TMC5 | EMILIN2 | PKN1 | ATAD3C | ASPHD2 | WTIP | LSP1 | SLC29A2 | EMP1 | PRIM1 |
| ZNF652 | TIMP2 | MIDN | SEC1P | TET3 | HYAL1 | LYPD2 | SH2D4A | BICDL1 | SGF29 |
| FAM3D-AS1 | MKNK2 | SERPINF1 | PLPP2 | LEFTY1 | PLCB3 | SLC16A3 | CAPN12 | PTPRH | MAL |
| GMPR | SPTBN2 | ENO1 | SLC9A3R2 | FAM107B | SLC12A5 | HEXB | R3HDM2 | SLC9A1 | SLC25A37 |
| ATG16L2 | NDUFA4L2 | VWF | ECI1 | CREBBP | KRT23 | TNFSF14 | MUC16 | MIB2 | WNT3A |
| EPHA8 | SNHG17 | KRT8 | FASN | S100P | CAPNS1 | SH3GL3 | ATP2A1 | MED24 | MROH6 |
| FBP1 | RAB26 | KRT78 | UPP1 | APOL6 | IFI27 | TLCD1 | NQO2 | PTPRD | BEST1 |
| SIX1 | CYBA | MOCOS | RNF223 | EEF1A2 | DGUOK-AS1 | TBC1D1 | SLC6A8 | FAM120A | ARRB2 |
| MRPL12 | CRMP1 | FIBCD1 | FBXL19 | P4HTM | TMCO4 | TIMM44 | PPP2CB | CRIP1 | VEGFA |
| TMEM205 | MCRIP2 | MT1M | TMEM164 | RASGRP2 | MSI1 | C15orf39 | MAP4K1 | KLK13 | N4BP3 |
| KLF16 | VKORC1 | LGALS9C | LEMD1 | ALMS1 | TF | SLC7A1 | RASA4B | FAM3D | NXPH4 |
| MYEOV | TET2 | LRRC56 | DCTPP1 | LGALS9 | ABCA4 | WNT6 | SGMS1-AS1 | PDXP | DUSP5 |
| H19 | IZUMO4 | ||||||||
| Downregulated genes with reduced 5hmC peaks in Promoter regions in TET2 KD cells | |||||||||
| INF2 | HGD | PRR34-AS1 | B4GALT5 | EIF4EBP3 | CYSRT1 | LSP1 | KRT78 | SERPINF1 | LYPD2 |
| KRT8 | RAB26 | TLCD1 | NQO2 | ARRB2 | FAM107A | SPTBN2 | PTPRH | CSK | NAT14 |
| TJP3 | SLC4A2 | LEFTY1 | PCYT2 | MLPH | TMCO4 | LGALS9C | TMEM205 | CAPS | UPP1 |
| IFI27 | MAL | LRRC56 | MYEOV | CCDC88B | JDP2 | UBXN10 | S100P | SGMS1-AS1 | N4BP3 |
| GMPR | CARD10 | RHBDL1 | IZUMO4 | SMDT1 | |||||