Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Plasmid DNA cleavage induced by wild-type (blue), GyrAS83L (red), GyrAD87N (green), and GyrAS83L/D87N (black) gyrase enzymes in the presence of 0–20 µM ciprofloxacin (left) or quinazolinedione (right). Mg2+ was the metal ion. The inset in the left panel shows the level of cleavage induced by the enzymes in the presence of 500 µM ciprofloxacin. Error bars represent the standard deviation of three or more independent experiments.
