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. 2023 Feb 1;24(3):2791. doi: 10.3390/ijms24032791

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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XIAP expression in the spinal cord of CB57^WT and CB57^hXIAP+ mice was reduced after SCI. Representative immunoblot of XIAP levels in CB57^WT (A) and hXIAP in both CB57^WT and CB57^hXIAP+ (C) mouse spinal cord samples. Band densitometry (relativised to the loading control) reveals that SCI induces a decrease in endogenous XIAP and human hXIAP expression in CB57^WT (B) and CB57^hXIAP+ (D) mice, respectively (* = p-value < 0.05 in Student’s t-test n = 3–4 animals/group).