Table 4.
Last follow-up changes of eGFR categories in respect to baseline uDKK3 #.
| Baseline | Latest Follow-Up | |||||
|---|---|---|---|---|---|---|
| eGFR Categories (mL/min/1.73 m2) | Patients with Baseline uDKK ≥ 400 pg/mg Creatinine (n = 11) | Patients with Baseline uDKK < 400 pg/mg Creatinine (n = 20) | p-Value ° | Patients with Baseline uDKK ≥ 400 pg/mg Creatinine (n = 11) | Patients with Baseline uDKK < 400 pg/mg Creatinine (n = 20) | p-Value + |
| >90 | 2 (18%) | 7 (35%) | 0.0304 * | 1 (9%) | 8 (40%) | 0.0808 |
| 60–89 | 4 (36%) | 8 (40%) | 3 (27%) | 6 (30%) | ||
| 30–59 | 1 (9%) | 5 (25%) | 2 (18%) | 5 (25%) | ||
| 15–29 | 4 (36%) | 0 (0%) | 3 (27%) | 1 (5%) | ||
| <15 | 0 (0%) | 0 (0%) | 2 (18%) | 0 (0%) | ||
| Decrease in eGFR category | - | - | 6 (55%) | 4 (20%) | 0.049 * | |
# eGFR—estimated glomerular filtration rate, uDKK3—urinary Dickkopf-3. Values represent n (%). p-values are based on the comparison of patients with an uDKK3 level above or below 400 pg/mg creatinine (° at baseline, + at latest follow-up). * marks significant values.