Figure 1.

Effect of the HFD and MED on liver histology of Golden Syrian hamsters. (A) Outline of the experimental design. (B) Steatosis score of histological changes in the liver. Differences were detected using Fisher’s exact test (* p-value < 0.05, ** p-value < 0.001). (C–E) Histological analysis of steatosis in liver sections stained with Hematoxylin and Eosin (400×). (F) Relative hepatic lipid content of hamsters in experimental groups. CTRL, normal diet; HFD, high-fat diet; MED, Mediterranean-like diet. Differences among groups in hepatic total lipid content were detected by Student t-test. All results were considered statistically significant at p-value < 0.05.