Table 2.
Variables | Quartiles of SIRI | p Value | |||
---|---|---|---|---|---|
Q1 | Q2 | Q3 | Q4 | ||
Participants, n | 10,684 | 10,732 | 10,725 | 10,734 | |
Age, years | 43.05 (17.06) | 43.98 (17.48) | 44.58 (17.99) | 46.19 (19.47) | <0.001 |
Male, % | 4616 (43.2) | 5031 (46.9) | 5429 (50.6) | 6007 (56.0) | <0.001 |
Race/ethnicity, % | <0.001 | ||||
Mexican American | 1797 (16.8) | 2340 (21.8) | 2297 (21.4) | 2144 (20.0) | |
Other Hispanic | 828 (7.7) | 1013 (9.4) | 975 (9.1) | 911 (8.5) | |
Non-Hispanic White | 2642 (24.7) | 4105 (38.3) | 4834 (45.1) | 5448 (50.8) | |
Non-Hispanic Black | 4075 (38.1) | 2154 (20.1) | 1645 (15.3) | 1413 (13.2) | |
Other race | 1342 (12.6) | 1120 (10.4) | 974 (9.1) | 818 (7.6) | |
Education level, % | <0.001 | ||||
Below high school | 2795 (26.2) | 2969 (27.7) | 2941 (27.4) | 3010 (28.0) | |
High school | 2229 (20.9) | 2352 (21.9) | 2400 (22.4) | 2652 (24.7) | |
Above high school | 5660 (53.0) | 5411 (50.4) | 5384 (50.2) | 5072 (47.3) | |
Poverty, % | 2348 (22.0) | 2270 (21.2) | 2258 (21.1) | 2367 (22.1) | 0.150 |
Smoking status, % | <0.001 | ||||
Never smokers | 6897 (64.6) | 6473 (60.3) | 6151 (57.4) | 5387 (50.2) | |
Former smokers | 1905 (17.8) | 2203 (20.5) | 2177 (20.3) | 2411 (22.5) | |
Current smokers | 1882 (17.6) | 2056 (19.2) | 2397 (22.3) | 2936 (27.4) | |
Drinking status, % | <0.001 | ||||
Non-drinkers | 2716 (25.4) | 2381 (22.2) | 2281 (21.3) | 2176 (20.3) | |
Low-to-moderate drinkers | 7273 (68.1) | 7598 (70.8) | 7611 (71.0) | 7523 (70.1) | |
Heavy drinkers | 695 (6.5) | 753 (7.0) | 833 (7.8) | 1035 (9.6) | |
BMI status, % | <0.001 | ||||
<25.0 | 3898 (36.5) | 3469 (32.3) | 3220 (30.0) | 3285 (30.6) | |
25.0–29.9 | 3501 (32.8) | 3616 (33.7) | 3541 (33.0) | 3429 (31.9) | |
>29.9 | 3285 (30.7) | 3647 (34.0) | 3964 (37.0) | 4020 (37.5) | |
Physical activity, % | <0.001 | ||||
Inactive | 2520 (23.6) | 2560 (23.9) | 2549 (23.8) | 2882 (26.8) | |
Insufficiently active | 3927 (36.8) | 4078 (38.0) | 4084 (38.1) | 3968 (37.0) | |
Active | 4237 (39.7) | 4094 (38.1) | 4092 (38.2) | 3884 (36.2) | |
Energy intake, kcal/day | 1913.00 [1439.00, 2503.00] | 1955.05 [1467.00, 2570.38] | 1977.00 [1496.68, 2586.00] | 1999.00 [1498.00, 2631.97] | <0.001 |
eGFR, ml/min/1.73 m2 | 103.09 (22.07) | 100.83 (22.09) | 99.40 (23.06) | 96.91 (25.30) | <0.001 |
ALT, U/L | 20.00 [15.00, 27.00] | 21.00 [16.00, 29.00] | 21.00 [16.00, 29.00] | 21.00 [16.00, 29.00] | <0.001 |
AST, U/L | 22.00 [19.00, 27.00] | 22.00 [19.00, 27.00] | 22.00 [19.00, 27.00] | 22.00 [19.00, 27.00] | 0.902 |
Hypertension, % | 2642 (24.7) | 2718 (25.3) | 2860 (26.7) | 3374 (31.4) | <0.001 |
Diabetes, % | 796 (7.5) | 908 (8.5) | 941 (8.8) | 1131 (10.5) | <0.001 |
WBC count, 103/μL | 5.50 [4.70, 6.50] | 6.50 [5.60, 7.60] | 7.30 [6.30, 8.50] | 8.60 [7.30, 10.10] | <0.001 |
Neutrophils count, 103/μL | 2.70 [2.20, 3.20] | 3.60 [3.10, 4.20] | 4.40 [3.70, 5.10] | 5.60 [4.70, 6.70] | <0.001 |
Monocyte count, 103/μL | 0.40 [0.30, 0.50] | 0.50 [0.40, 0.60] | 0.60 [0.50, 0.70] | 0.70 [0.60, 0.80] | <0.001 |
Lymphocyte count, 103/μL | 2.20 [1.80, 2.70] | 2.10 [1.70, 2.60] | 2.10 [1.70, 2.60] | 1.90 [1.50, 2.40] | <0.001 |
Platelet count, 103/μL | 239.00 [203.00, 281.00] | 246.00 [210.00, 289.00] | 251.00 [214.00, 296.00] | 258.50 [218.00, 305.00] | <0.001 |
SII | 291.19 [219.20, 375.67] | 413.77 [332.81, 518.14] | 523.89 [422.93, 653.14] | 748.52 [590.89, 983.48] | <0.001 |
Normally distributed continuous variables were described as means and SD, and continuous variables without a normal distribution were presented as medians [interquartile ranges]. Categorical variables were presented as numbers (percentages). eGFR, estimated glomerular filtration rate; ALT, alanine aminotransferase; AST, aspartate aminotransferase; WBC, white blood cell; SII, systemic immune-inflammatory index; SIRI, systemic inflammatory response index.