Table 3.

HRs (95% Cis) of cardiovascular diseases and all-cause mortalities according to quartiles of SII among the general adult population in NHANES, 1999–2018.

	Q1	Q2	Q3	Q4	p Trend
Levels of SII	<335.36	355.36–468.83	468.84–655.55	>655.56
Cardiovascular mortality
No. deaths/total	203/10,718	222/10,720	249/10,720	324/10,717
Crude	Reference	1.00 (0.83–1.21)	1.05 (0.88–1.27)	1.32 (1.11–1.57)	0.002
Model 1	Reference	1.12 (0.92–1.35)	1.20 (0.99–1.45)	1.43 (1.19–1.71)	0.001
Model 2	Reference	1.09 (0.90–1.32)	1.16 (0.96–1.40)	1.33 (1.11–1.59)	0.015
All-cause mortality
No. deaths/total	897/10,718	923/10,720	1008/10,720	1422/10,717
Crude	Reference	0.94 (0.86–1.03)	0.97 (0.88–1.06)	1.31 (1.21–1.43)	<0.001
Model 1	Reference	1.01 (0.92–1.11)	1.05 (0.96–1.15)	1.38 (1.26–1.50)	<0.001
Model 2	Reference	0.99 (0.91–1.09)	1.03 (0.94–1.13)	1.29 (1.18–1.41)	<0.001

Data are presented as HR (95% CI) unless indicated otherwise.