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. 2023 Jan 24;12(3):921. doi: 10.3390/jcm12030921

Table 5.

Multivariate logistic regression models with symptoms of anemia as outcome variables (weighted).

Outcomes
Fatigue Lack of Energy Lack of Concentration Dyspnea and/or Weakness
Predictors OR (95% CI)
n = 5957
OR (95% CI)
n = 5957
OR (95% CI)
n = 5957
OR (95% CI)
n = 5957
Model 1 Model 2 Model 1 Model 2 Model 1 Model 2 Model 1 Model 2
Anemia 1.15
(0.94; 1.40)
1.19
(0.98; 1.46)
1.41
(1.09; 1.81)
1.45
(1.13; 1.86)
1.12
(0.87; 1.44)
1.13
(0.88; 1.46)
1.04
(0.85; 1.29)
1.11
(0.90; 1.37)
Women 1.40
(1.26; 1.55)
1.42
(1.28; 1.57)
1.33
(1.16; 1.52)
1.33
(1.16; 1.53)
1.12
(0.98; 1.28)
1.11
(0.97; 1.28)
1.08
(0.97; 1.21)
1.09
(0.98; 1.22)
Age (years) 0.98
(0.97; 0.99)
0.98
(0.98; 0.99)
0.98
(0.97; 0.99)
0.99
(0.98; 1.00)
1.01
(1.00; 1.01)
1.01
(1.00; 1.02)
1.01
(1.01; 1.02)
1.03
(1.02; 1.04)
Number of medications 1.11
(1.08; 1.13)
- 1.13
(1.09; 1.16)
- 1.08
(1.05; 1.10)
- 1.19
(1.17; 1.22)
-
Medication with possible side effect fatigue - 1.25
(1.10; 1.42)
- 1.58
(1.36; 1.85)
- 1.70
(1.47; 1.98)
- 1.69
(1.49; 1.92)
Depression and/or anxiety (SHIP) 3.44
(3.08; 3.84)
3.49
(3.13; 3.91)
8.22
(7.22; 9.36)
8.13
(7.14; 9.26)
6.79
(5.95; 7.74)
6.58
(5.77; 7.51)
2.66
(2.36; 2.99)
2.68
(2.38; 3.01)
Insomnia (SHIP) 2.24
(2.01; 2.49)
2.31
(2.08; 2.57)
2.06
(1.80; 2.35)
2.12
(1.86; 2.43)
1.76
(1.54; 2.02)
1.78
(1.56; 2.04)
1.65
(1.47; 1.84)
1.72
(1.54; 1.93)
CCI (claims data) 1.10
(1.04; 1.16)
1.18
(1.12; 1.25)
1.07
(0.99; 1.14)
1.15
(1.08; 1.22)
1.08
(1.01; 1.15)
1.11
(1.04; 1.18)
1.09
(1.03; 1.16)
1.20
(1.14; 1.27)
Heart failure (claims data) - - - - - - 2.66
(1.7; 4.00)
3.03
(2.03; 4.53)
COPD (claims data) - - - - - - 1.99
(1.49; 2.65)
2.14
(1.61; 2.83)
Asthma (claims data) - - - - - - 3.36
(2.67; 4.25)
3.63
(2.88; 4.56)

OR: odds ratio, 95% CI: 95% confidence interval, CCI: Charlson Comorbidity Index, COPD: chronic obstructive pulmonary disease, SHIP: Study of Health in Pomerania. Bold numbers = statistically significant.