Table 5.
Outcomes | ||||||||
---|---|---|---|---|---|---|---|---|
Fatigue | Lack of Energy | Lack of Concentration | Dyspnea and/or Weakness | |||||
Predictors |
OR (95% CI)
n = 5957 |
OR (95% CI)
n = 5957 |
OR (95% CI)
n = 5957 |
OR (95% CI)
n = 5957 |
||||
Model 1 | Model 2 | Model 1 | Model 2 | Model 1 | Model 2 | Model 1 | Model 2 | |
Anemia | 1.15 (0.94; 1.40) |
1.19 (0.98; 1.46) |
1.41
(1.09; 1.81) |
1.45
(1.13; 1.86) |
1.12 (0.87; 1.44) |
1.13 (0.88; 1.46) |
1.04 (0.85; 1.29) |
1.11 (0.90; 1.37) |
Women |
1.40
(1.26; 1.55) |
1.42
(1.28; 1.57) |
1.33
(1.16; 1.52) |
1.33
(1.16; 1.53) |
1.12 (0.98; 1.28) |
1.11 (0.97; 1.28) |
1.08 (0.97; 1.21) |
1.09 (0.98; 1.22) |
Age (years) | 0.98 (0.97; 0.99) |
0.98 (0.98; 0.99) |
0.98 (0.97; 0.99) |
0.99 (0.98; 1.00) |
1.01 (1.00; 1.01) |
1.01 (1.00; 1.02) |
1.01
(1.01; 1.02) |
1.03
(1.02; 1.04) |
Number of medications |
1.11
(1.08; 1.13) |
- |
1.13
(1.09; 1.16) |
- |
1.08
(1.05; 1.10) |
- |
1.19
(1.17; 1.22) |
- |
Medication with possible side effect fatigue | - |
1.25
(1.10; 1.42) |
- |
1.58
(1.36; 1.85) |
- |
1.70
(1.47; 1.98) |
- |
1.69
(1.49; 1.92) |
Depression and/or anxiety (SHIP) |
3.44
(3.08; 3.84) |
3.49
(3.13; 3.91) |
8.22
(7.22; 9.36) |
8.13
(7.14; 9.26) |
6.79
(5.95; 7.74) |
6.58
(5.77; 7.51) |
2.66
(2.36; 2.99) |
2.68
(2.38; 3.01) |
Insomnia (SHIP) |
2.24
(2.01; 2.49) |
2.31
(2.08; 2.57) |
2.06
(1.80; 2.35) |
2.12
(1.86; 2.43) |
1.76
(1.54; 2.02) |
1.78
(1.56; 2.04) |
1.65
(1.47; 1.84) |
1.72
(1.54; 1.93) |
CCI (claims data) |
1.10
(1.04; 1.16) |
1.18
(1.12; 1.25) |
1.07 (0.99; 1.14) |
1.15
(1.08; 1.22) |
1.08 (1.01; 1.15) |
1.11
(1.04; 1.18) |
1.09
(1.03; 1.16) |
1.20
(1.14; 1.27) |
Heart failure (claims data) | - | - | - | - | - | - |
2.66
(1.7; 4.00) |
3.03
(2.03; 4.53) |
COPD (claims data) | - | - | - | - | - | - |
1.99
(1.49; 2.65) |
2.14
(1.61; 2.83) |
Asthma (claims data) | - | - | - | - | - | - |
3.36
(2.67; 4.25) |
3.63
(2.88; 4.56) |
OR: odds ratio, 95% CI: 95% confidence interval, CCI: Charlson Comorbidity Index, COPD: chronic obstructive pulmonary disease, SHIP: Study of Health in Pomerania. Bold numbers = statistically significant.