Table 1.
Functionality comparison of popular free CGM analysis software
| GlyCulator | iglu | cgm-analysis | CGDA | rGV | cgm-quantify | CGM-Stats-Analyzer | CGM-Shiny | GLU | CGM-analyzer | CGMTSA | GVAP | EasyGV | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Glycemic variability | |||||||||||||
| Number of days CGM worn | X | X | X | X | X | ||||||||
| Active time % | X | X | X | X | X | ||||||||
| Mean glucose | X | X | X | X | X | X | X | X | X | X | X | ||
| Glucose management indicator | X | X | X | X | X | X | |||||||
| Glycemic variability (%CV) | X | X | X | X | X | X | X | ||||||
| Time above/in/below range | X | X | X | X | X | X | |||||||
| Ambulatory glucose profile | X | X | |||||||||||
| Day and night | X | X | X | X | |||||||||
| File upload | |||||||||||||
| Medtronic CareLink Pro/Personal | X | X | X | X | X | X | X | ||||||
| Abbott Libre/LibreView/CoPilot | X | X | X | X | X | X | X | ||||||
| Dexcom Studio/Clarity; diasend | X | X | X | X | X | X | |||||||
| Roche Accu-Check Smart Pix (Eversense/Ascensia) | X | X | |||||||||||
| User defined | X | X | X | X | X | ||||||||
| Software defined | X | X | X | X | X | X | X | ||||||
| File preparation | |||||||||||||
| Period selection for analysis | X | ||||||||||||
| Date–time format detection | X | X | X | ||||||||||
| Quality control | X | ||||||||||||
| Missing data imputation | X | X | X | X | X | X | X | X | |||||
| Multiple file processing | X | X | X | X | X | X | X | X | X | ||||
| Many-to-single file merge | X | ||||||||||||
| Sharing and access | |||||||||||||
| Data anonymization and storage | X | ||||||||||||
| Analysis sharing | X | ||||||||||||
| Graphical user interface | X | X | X | X | X | ||||||||
| Online platform | X | X | X | X | |||||||||
| Programmatic access | Python | R | R | R | R | R/Python | R | R | R | MATLAB | |||
| Source publication/code repository | This article | 10.1371/journal.pone.0248560 | 10.1371/journal.pone.0216851 | 10.1177/19322968211070293 | 10.1177/19322968211028909 | 10.1109/OJEMB.2021.3105816 | 10.1177/1932296820985570 | https://github.com/rolandhangelbroek/cgmshiny | 10.1093/ije/dyaa004 | 10.1093/bioinformatics/btx826 | 10.1101/2020.07.06.174748 | 10.1186/s12938-015-0035-3 | 10.1089/dia.2010.0247 |
Xs represent functionalities implemented. Exact workings of specific functions may differ, but if a specific function was present in any extent we marked it as present. The following tools were omitted because of lack of continued support, inaccessibility through links/websites of original publications, or restricted or paid access: CGM-GUIDE, wiseCGM, hamsamilton/cgms.analysis, Glooko. URLs for the evaluated tools for which an online platform is provided and maintained (accessed 29 August 2022): GlyCulator (https://glyculator.btm.umed.pl/); rGV (https://shiny.biostat.umn.edu/GV/); iglu (https://irinagain.shinyapps.io/shiny_iglu/); CGMStatsAnalyser (https://baker-biostats.shinyapps.io/CGMStatsAnalyser/). CGDA, Continuous Glucose Data Analysis; CV, coefficient of variation; GVAP, Glycemic Variability Analyzer Program.