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. 2023 Feb 10;9:56. doi: 10.1038/s41420-023-01355-8

Table 1.

Relationship between NAT10 expression level and clinical characteristics of HCC patients.

Clinical features Number NAT10 Positive rate (%) Z/χ2 P
Negative Low High
Sex 0.265 0.791
 Male 80 6 28 46 92.5
 Female 20 2 7 11 90.0
Age 0.542 0.588
 ≤60 years 48 2 18 28 95.8
 >60 years 52 6 17 29 88.5
History of hepatitis 7.217 0.027*
 Positive 76 3 27 46 96.0
 Negative 24 5 8 11 79.0
History of cirrhosis 8.371 0.015*
 Positive 78 3 29 46 96.2
 Negative 22 5 6 11 77.3
Tumor size 1.139 0.255
 ≤5 cm 59 5 23 31 91.5
 >5 cm 40 3 11 26 92.5
Differentiation 2.166 0.339
 Low 30 2 13 15 93.3
 Middle 64 6 21 37 90.6
 High 6 0 1 5 100.0
Single/Multiple tumor 1.416 0.157
 Single 83 8 30 45 90.4
 Multiple 17 0 5 12 100.0
AFP 0.987 0.324
 Normal 43 6 14 23 86.0
 Abnormal 57 2 21 34 96.5
ALT 1.296 0.195
 Normal 35 2 10 23 94.3
 Abnormal 65 6 25 34 90.8
AST 0.304 0.761
 Normal 40 4 12 24 90.0
 Abnormal 60 4 23 33 93.3

NAT10 N-acetyltransferase 10, AFP alpha-fetoprotein, ALT alanine aminotransferase, AST aspartate aminotransferase.

*p value <0.05.