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. 2023 Feb 10;14:755. doi: 10.1038/s41467-023-36089-9

Fig. 2. BSH-producing Bacteroides species are enriched in a CRC mouse model.

Fig. 2

a–g Apcf/w and Cdx2Apcf/w mice were fed a HFD for 12 weeks (n = 8 mice for Apcf/w; n = 5 mice for Cdx2Apcf/w). a Representative pictures of ileum and colon, revealing the tumor occurrence (in red circle). b Tumor numbers in different segments of intestine from 5 Cdx2Apcf/w mice, Duo: duodenum; Jeju: jejunum; Ile: Ileum. c Length of small intestine and colon. d Top 15 species of gut microbiota that led to the differences between two groups. e Relative abundance of variable gut microbiota species levels. Kruskal–Wallis test with Dunn’s post hoc test. f bsh hits in the variable gut microbiota species. g Unconjugated bile acid profiles in the colon contents. Mann–Whitney U test with two-sided. ωMCA: ω-muricholic acid. Data are presented as mean values +/– SEM in (b, c, e, g). Source data are provided as a Source Data File for Fig. 2.