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. 2023 Feb 10;13:2384. doi: 10.1038/s41598-023-29596-8

Table 2.

Summary statistics of the significant SNPs (p-value < 0.05) in SNP-exposure association.

SNP CHR Position REF ALT Nearby Gene Beta SE p_value Explained variance F-statistics
rs3755967 4 72,609,398 C T GC − 0.10037 0.011 1.78 × 10−20 0.0169 86.02529
rs10832254 11 14,434,698 A G COPB1 − 0.08010 0.009 3.23 × 10−17 0.0139 71.20003
rs12803256 11 71,132,868 A G ACTE1P 0.05003 0.011 1.96 × 10−06 0.0045 22.63105
rs2144530 14 39,552,484 C T SEC23A − 0.03662 0.010 0.000282 0.0025 13.18342
rs3814995 19 36,342,212 C T NPHS1 − 0.03342 0.010 0.000605 0.0023 11.75963
rs1229984 4 100,239,319 T C ADH1B 0.03333 0.011 0.00261945 0.0018 9.05529
rs4575545 16 79,755,446 G A MAFTRR, LINC01229 − 0.03249 0.011 0.00276995 0.0018 8.95309
rs6724965 2 101,440,151 A G NPAS2 − 0.02837 0.010 0.00295511 0.0017 8.83494
rs7519574 1 34,726,552 G A C1orf94 − 0.07541 0.027 0.00514931 0.0017 7.82622
rs8121940 20 52,742,306 C G BCAS1, CYP24A1 − 0.04614 0.017 0.00648466 0.0015 7.41040
rs2012736 2 234,622,379 C A UGT1A5 − 0.03686 0.014 0.00838168 0.0014 6.95009
rs8091117 18 28,919,794 C A DSG1 − 0.05525 0.022 0.0134677 0.0012 6.10659
rs35823191 1 17,560,123 T C PADI1 − 0.02786 0.013 0.0320312 0.0009 4.59680
rs11732896 4 88,287,993 G A HSD17B11 − 0.02169 0.010 0.0344214 0.0009 4.47363

Chr Chromosome position: Chromosomal Position (hg19), REF Reference allele, ALT Alternative allele, SE Standard error, Approximate F-statistics which is calculated from the formula (beta/se)2.