Table 2:

Multivariate associations with the development of ALD

Variable	Odds Ratio	95% CI	P value
Age	1.01	1.00 to 1.02	0.04
Male Sex	1.20	1.01 to 1.43	0.04
Asian Race	2.29	0.97 to 4.51	0.03
Black Race	0.83	0.61 to 1.09	0.20
Other Race	0.97	0.63 to 1.43	0.90
Unknown Race	1.48	0.90 to 2.32	0.11
Hispanic Ethnicity	0.60	0.35 to 1.00	0.053
Overweight	0.96	0.78 to 1.17	0.68
Obese Class I	0.93	0.59 to 1.17	0.52
Obese Class II	0.83	0.59 to 1.15	0.28
Obese Class III	1.04	0.70 to 1.49	0.85
Missing Weight	0.79	0.58 to 1.05	0.11
Nicotine Dependence	1.10	0.93 to 1.31	0.28
Hep B Positive	1.08	0.74 to 1.56	0.67
Hep C Positive	2.17	1.79 to 2.63	<0.001
Homeless	1.25	1.01 to 1.56	0.04
Cannabis Use Disorder	1.18	0.95 to 1.45	0.13
Cocaine Use Disorder	0.73	0.58 to 0.92	0.009
Inhalant Use Disorder	0.87	0.70 to 1.09	0.24
Opioid Use Disorder	1.12	0.91 to 1.38	0.28
Other Stimulant Use Disorder	1.00	0.73 to 1.35	0.99
Sedative Use Disorder	1.03	0.80 to 1.32	0.81
Anxiety Disorder	1.30	1.04 to 1.65	0.03
Specific Personality Disorder	0.94	0.73 to 1.19	0.59
Mood Disorder	0.98	0.78 to 1.23	0.84
Schizophrenia	1.18	0.97 to 1.43	0.10
Chronic Passive Congestion of Liver	1.86	1.48 to 2.30	<0.001
Hemochromatosis	1.75	1.16 to 2.53	0.005
Autoimmune Hepatitis	1.05	0.33 to 2.69	0.92
Primary Biliary Cholangitis	0.20	0.05 to 1.20	0.04
Secondary Biliary Cholangitis	6.528	1.05 to 25.68	0.02
Biliary Cirrhosis	3.86	1.19 to 10.42	0.01
Alpha-1-antitrypsin Deficiency	3.38	0.56 to 10.66	0.09
Nonalcoholic Steatohepatitis	4.04	2.93 to 5.46	<0.001
Alcohol Dependence	1.18	0.81 to 1.69	0.37
Both Alcohol Abuse and Dependence	4.90	3.93 to 6.18	<0.001
Medication-assisted Therapy	0.56	0.47 to 0.66	<0.001
Psychotherapy	0.59	0.50 to 0.71	<0.001

Odds ratios for racial categories use white race as reference level, while BMI categories use the reference level of the non-overweight BMI class. AUD class (dependence, abuse or both) use alcohol abuse as a reference level.