FIGURE 2.

(A) UMAP demonstrating major olfactory epithelial cell types represented in the data. (B) Expression of Il4ra (log transformed). The absence of violin plots indicates that there are no cell types in which the majority of captured cells have nonzero expression. Each dot represents an individual cell, with SUS and OSN comprising a large proportion of captured cells in this data set. Cells above the x-axis express nonzero levels of IL-4ra1. (C) Expression of Il13ra1 (log transformed). Three non-neuronal cell types—SUS, BG, and MV—have violin plots showing nonzero expression of Il13ra1 in the majority of cells. OSNs do not have a violin plot and have a small number of cells with nonzero expression. Coexpression of both receptor subunits is necessary for a functional IL-13 receptor. BG, Bowman gland; GBC, globose basal cell; HBC, horizontal basal cell; iOSN, immature olfactory sensory neuron; INP, immediate neuronal precursor; MV, microvillar cell; OSN, olfactory sensory neuron; SUS, sustentacular cell; UMAP, uniform manifold approximation and projection