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. Author manuscript; available in PMC: 2023 Feb 11.
Published in final edited form as: Mult Scler. 2022 Oct 13;29(2):248–260. doi: 10.1177/13524585221127414

Table 1.

Sample Characteristics

Total Q1 Q2 Q3 Q4
n (%) 563 (100) 133 (23.6) 167 (29.7) 160 (28.4) 103 (18.3)
Age, mean (SD), y 44.2 (11.3) 43.4 (11.0) 42.2 (11.4) 45.9 (11.6) 45.9 (10.5)
Sex, n (%)
 Women 398 (70.7) 91 (68.4) 107 (64.1) 121 (75.6) 79 (76.7)
 Men 165 (29.3) 52 (31.6) 60 (35.9) 39 (24.4) 24 (23.3)
Race and Ethnicity, n (%)
 Black (non-Hispanic) 101 (17.9) 46 (34.6) 20 (12) 26 (16.3) 9 (8.7)
 Hispanic 90 (16.0) 33 (24.8) 34 (20.4) 15 (9.4) 8 (7.8)
 White (non-Hispanic) 357 (63.4) 51 (38.3) 108 (64.7) 115 (71.9) 83 (80.6)
 Other / Unknown 15 (2.7) 3 (2.3) 5 (3) 4 (2.5) 3 (2.9)
Socioeconomic Status Index, mean (SD) 53.6 (18.6) 43.6 (18.0) 53.1 (19.2) 58.4 (16.0) 60.0 (16.9)
 Educational Attainment, aggregate years 15.1 (2.0) 14.5 (2.0) 15.0 (2.1) 15.4 (1.8) 15.5 (2.)
 WTAR raw 37.5 (8.6) 33.2 (9.6) 37.4 (7.9) 39.5 (7.2) 40.2 (8.0)
 AHRQ Index 56.1 (2.8) 55.0 (2.5) 56.0 (2.8) 56.7 (2.7) 56.8 (2.7)
Time since diagnosis, mean (SD), years 8.89 (7.80) 9.47 (7.89) 8.93 (7.79) 8.23 (7.85) 9.09 (7.66)
Disease Course, n (%)
 Relapsing Remitting 441 (78.3) 94 (70.7) 137 (82) 130 (81.3) 80 (77.7)
 Primary Progressive 35 (6.2) 10 (7.5) 6 (3.6) 11 (6.9) 8 (7.8)
 Secondary Progressive 87 (15.5) 29 (21.8) 24 (14.4) 19 (11.9) 15 (14.6)
Disease Modifying Therapy type, n (%)
 None 95 (16.9) 23 (17.3) 23 (13.8) 32 (20) 17 (16.5)
 Injection 75 (13.3) 14 (10.5) 24 (14.4) 15 (9.4) 22 (21.4)
 Oral 172 (30.6) 38 (28.6) 49 (29.3) 57 (35.6) 28 (27.2)
 Infusion 221 (39.3) 58 (43.6) 71 (42.5) 56 (35) 36 (35)
Health-Related Covariates, n (%)
 BMI, mean (SD) 27.1 (5.9) 28.3 (6.0) 27.0 (5.8) 26.9 (6.1) 25.8 (5.3)
 MVPA, mean (SD) 21.7 (22.2) 12.1 (19.0) 21.1 (22.4) 24.7 (20.5) 30.2 (23.8)
 Sleep Disturbance 251 (44.6) 67 (50.4) 75 (44.9) 66 (41.3) 43 (41.7)
 Hypertension 98 (17.4) 25 (18.8) 31 (18.6) 29 (18.1) 13 (12.6)
 Diabetes 23 (4.1) 7 (5.3) 11 (6.6) 4 (2.5) 1 (1)
 Hyperlipidemia 102 (18.1) 23 (17.3) 37 (22.2) 25 (15.6) 17 (16.5)
 Smoking 179 (31.8) 48 (36.1) 44 (26.3) 49 (30.6) 38 (36.9)
Unadjusted Outcomes, mean (SD)
 MSFC z-score −1.12 (1.22) −1.75 (1.35) −1.07 (1.14) −0.90 (1.14) −0.72 (0.97)
 SDMT raw 51.1 (12.0) 45.9 (13.2) 51.5 (11.5) 53.2 (11.3) 53.7 (10.2)
 NHPT raw 23.4 (5.5) 25.8 (6.1) 23.6 (5.2) 22.5 (5.3) 21.7 (4.6)
 T25FW raw 4.99 (1.34) 5.64 (1.44) 4.85 (1.33) 4.83 (1.16) 4.61 (1.20)
 MSISphys raw 39.71 (18.2) 46.2 (19.6) 39.2 (19.0) 38.2 (16.7) 34.6 (14.7)
 FSS raw 3.67 (1.92) 4.15 (1.86) 3.79 (2.00) 3.53 (1.91) 3.09 (1.72)
 MSWS raw 40.5 (23.9) 49.6 (24.9) 39.0 (23.9) 39.0 (22.9) 33.7 (21.1)
 PDQ raw 1.43 (0.99) 1.67 (1.05) 1.49 (0.99) 1.34 (0.98) 1.20 (0.88)
 HADS-D raw 4.44 (3.64) 5.76 (3.74) 4.36 (3.83) 4.28 (3.39) 3.15 (3.05)
 HADS-A raw 7.16 (4.13) 7.80 (4.51) 7.31 (4.29) 7.02 (3.83) 6.30 (3.66)
Mediterranean Diet Adherence
 MEDAS, mean (SD) 6.25 (2.35) 3.08 (1.01) 5.54 (0.50) 7.46 (0.50) 9.61 (0.81)
 MEDAS, minimum, maximum 1, 12 1, 4 5, 6 7, 8 9, 12
Component criteria met, n (%)
 Olive oil is primary cooking fat 373 (66.3) 44 (33.1) 107 (64.1) 131 (81.9) 91 (88.3)
 Olive oil consumption ≥4 tbsp. / day 36 (6.4) 2 (1.5) 9 (5.4) 10 (6.3) 15 (14.6)
 Vegetable serving (200g/d) ≥2 / day 279 (49.6) 18 (13.5) 59 (35.3) 103 (64.4) 99 (96.1)
 Fruit serving (80g) ≥3 / day 91 (16.2) 4 (3) 12 (7.2) 34 (21.3) 41 (39.8)
 Red meat, sausage (100–150g) <1 / day 345 (61.3) 36 (27.1) 104 (62.3) 118 (73.8) 87 (84.5)
 Butter (12g) <1 / day 384 (68.2) 48 (36.1) 11 (65.9) 133 (83.1) 93 (90.3)
 Sugary drinks (12oz) <1 / day 430 (76.4) 64 (48.1) 119 (71.3) 144 (90) 103 (100)
 Wine (125ml) ≥7 / week 100 (17.8) 4 (3) 19 (11.4) 31 (19.4) 46 (44.7)
 Legumes (150g) ≥3 / week 89 (15.8) 2 (1.5) 11 (6.6) 27 (16.9) 49 (47.6)
 Fish (100–150g) ≥3 / week 91 (16.2) 2 (1.5) 22 (13.2) 29 (18.1) 38 (36.9)
 Commercial pastries <1 / week 272 (48.3) 30 (22.6) 65 (38.9) 97 (60.6) 80 (77.7)
 Nuts (30g) ≥2 / week 236 (41.9) 18 (13.5) 55 (32.9) 91 (56.9) 72 (69.9)
 Eat chicken or turkey more than pork, hamburger, or sausage 456 (81.0) 81 (60.9) 140 (83.8) 143 (89.4) 92 (89.3)
 Vegetables, pasta, or rice with garlic, tomato, or onion ≥2 / week 334 (59.3) 55 (41.4) 93 (55.7) 102 (63.8) 84 (81.6)