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. Author manuscript; available in PMC: 2023 Feb 11.
Published in final edited form as: Mult Scler. 2022 Oct 13;29(2):248–260. doi: 10.1177/13524585221127414

TABLE 3.

Relationship between Mediterranean Diet Adherence (MEDAS) and Outcomes

A. Hierarchical Regression Predicting MSFC with MEDAS and Covariates
Results are presented across models predicting MSFC with MEDAS adjusting for age and sex alone (F[3, 559]=57.08, p<0.001, R2=0.234), all demographic covariates (F[6, 556]=46.24, p<0.001, R2=0.333), and all demographic and health-related covariates (F[13, 549]=22.80, p<0.001, R2=0.351).
Predictor B 95% CI β p B 95% CI β p B 95% CI β p
Constant −0.797 −1.308 −0.286 0.002 −1.552 −2.074 −1.030 <0.001 −1.655 −2.368 −0.941 <0.001
MEDAS 0.164 0.126 0.202 0.32 <0.001 0.100 0.062 0.138 0.19 <0.001 0.095 0.055 0.134 0.18 <0.001
AGE −0.041 −0.049 −0.033 −0.38 0.001 −0.045 −0.052 −0.037 −0.41 <0.001 −0.046 −0.054 −0.038 −0.43 <0.001
SEX 0.279 0.083 0.474 0.10 0.005 0.330 0.146 0.514 0.12 <0.001 0.381 0.194 0.569 0.14 <0.001
RACE 0.390 0.182 0.598 0.15 <0.001 0.422 0.209 0.634 0.16 <0.001
ETHN 0.135 −0.109 0.379 0.04 0.278 0.151 −0.095 0.396 0.05 0.228
SES 0.017 0.012 0.022 0.27 <0.001 0.017 0.012 0.022 0.26 <0.001
BMI 0.004 −0.011 0.020 0.02 0.570
MVPA 0.002 −0.002 0.006 0.04 0.235
SLEEP −0.187 −0.358 −0.017 −0.08 0.032
HTN 0.212 −0.034 0.458 0.07 0.091
DM −0.090 −0.531 0.350 −0.02 0.687
HLD 0.135 −0.099 0.368 0.04 0.258
SMOKE −0.142 −0.327 0.043 −0.05 0.131
B. Fully-Adjusted Outcomes across (a) MEDAS scores and (b) MEDAS quartiles
Multiple regression results (a) report relationships between MEDAS scores and outcomes adjusting for all demographic and health-related covariates. Analysis of covariance results (b) report differences in outcomes across MEDAS quartiles adjusting for all demographic and health-related covariates.
(a) Multiple Regression Results (b) Analysis of Covariance Results
Outcome B 95% CI β p F3,547 ηp2 p Q1: M [95% CI] Q2: M [95% CI] Q3: M [95% CI] Q4: M [95% CI]
MSFC 0.095 0.055 0.134 0.18 <0.001 7.86 0.041 <0.001 −1.48 [−1.67, −1.30] −1.15 [−1.30, −1.00] −0.96 [−1.12, −0.80] −0.84 [−1.04, −0.64]
SDMT 0.869 0.458 1.279 0.17 <0.001 5.44 0.029 0.001 47.9 [46.0, 49.8] 50.8 [49.2, 52.4] 52.8 [51.1, 54.4] 53.1 [51.0, 55.2]
NHPT −0.392 −0.584 −0.199 −0.17 <0.001 5.78 0.031 <0.001 24.9 [24.0, 25.8] 23.7 [23.0, 24.5] 22.8 [22.0, 23.6] 22.2 [21.2, 23.1]
T25FW −0.077 −0.121 −0.033 −0.14 0.001 5.28 0.028 0.001 5.34 [5.14, 5.55] 4.95 [4.77, 5.12] 4.89 [4.71, 5.06] 4.75 [4.53, 4.97]
MSISphys −0.993 −1.609 −0.377 −0.13 0.002 2.71 0.015 0.044 42.8 [40.0, 45.7] 39.7 [37.3, 42.1] 39.3 [36.8, 41.8] 36.4 [33.3, 39.5]
FSS −0.102 −0.170 −0.034 −0.13 0.003 2.70 0.015 0.045 3.91 [3.60, 4.22] 3.80 [3.53, 4.06] 3.61 [3.34, 3.88] 3.25 [2.91, 3.60]
MSWS −1.312 −2.108 −0.516 −0.13 0.001 3.70 0.020 0.012 45.4 [41.7, 49.1] 40.0 [36.9, 43.1] 40.1 [36.9, 43.3] 35.8 [31.8, 39.9]
PDQ −0.056 −0.091 −0.022 −0.13 0.001 2.27 0.012 0.079 1.55 [1.39, 1.71] 1.51 [1.38, 1.65] 1.37 [1.23, 1.51] 1.26 [1.09, 1.44]
HADS-D −0.234 −0.362 −0.105 −0.15 <0.001 4.53 0.024 0.004 5.23 [4.63, 5.82] 4.39 [3.89, 4.89] 4.45 [3.94, 4.97] 3.51 [2.86, 4.16]
HADS-A −0.190 −0.338 −0.042 −0.11 0.012 2.43 0.013 0.064 7.64 [6.95, 8.32] 7.38 [6.80, 7.95] 7.11 [6.52, 7.70] 6.26 [5.51, 7.01]