TABLE 3.
A. Hierarchical Regression Predicting MSFC with MEDAS and Covariates | |||||||||||||||
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Results are presented across models predicting MSFC with MEDAS adjusting for age and sex alone (F[3, 559]=57.08, p<0.001, R2=0.234), all demographic covariates (F[6, 556]=46.24, p<0.001, R2=0.333), and all demographic and health-related covariates (F[13, 549]=22.80, p<0.001, R2=0.351). | |||||||||||||||
Predictor | B | 95% CI | β | p | B | 95% CI | β | p | B | 95% CI | β | p | |||
Constant | −0.797 | −1.308 | −0.286 | 0.002 | −1.552 | −2.074 | −1.030 | <0.001 | −1.655 | −2.368 | −0.941 | <0.001 | |||
MEDAS | 0.164 | 0.126 | 0.202 | 0.32 | <0.001 | 0.100 | 0.062 | 0.138 | 0.19 | <0.001 | 0.095 | 0.055 | 0.134 | 0.18 | <0.001 |
AGE | −0.041 | −0.049 | −0.033 | −0.38 | 0.001 | −0.045 | −0.052 | −0.037 | −0.41 | <0.001 | −0.046 | −0.054 | −0.038 | −0.43 | <0.001 |
SEX | 0.279 | 0.083 | 0.474 | 0.10 | 0.005 | 0.330 | 0.146 | 0.514 | 0.12 | <0.001 | 0.381 | 0.194 | 0.569 | 0.14 | <0.001 |
RACE | 0.390 | 0.182 | 0.598 | 0.15 | <0.001 | 0.422 | 0.209 | 0.634 | 0.16 | <0.001 | |||||
ETHN | 0.135 | −0.109 | 0.379 | 0.04 | 0.278 | 0.151 | −0.095 | 0.396 | 0.05 | 0.228 | |||||
SES | 0.017 | 0.012 | 0.022 | 0.27 | <0.001 | 0.017 | 0.012 | 0.022 | 0.26 | <0.001 | |||||
BMI | 0.004 | −0.011 | 0.020 | 0.02 | 0.570 | ||||||||||
MVPA | 0.002 | −0.002 | 0.006 | 0.04 | 0.235 | ||||||||||
SLEEP | −0.187 | −0.358 | −0.017 | −0.08 | 0.032 | ||||||||||
HTN | 0.212 | −0.034 | 0.458 | 0.07 | 0.091 | ||||||||||
DM | −0.090 | −0.531 | 0.350 | −0.02 | 0.687 | ||||||||||
HLD | 0.135 | −0.099 | 0.368 | 0.04 | 0.258 | ||||||||||
SMOKE | −0.142 | −0.327 | 0.043 | −0.05 | 0.131 |
B. Fully-Adjusted Outcomes across (a) MEDAS scores and (b) MEDAS quartiles | ||||||||||||
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Multiple regression results (a) report relationships between MEDAS scores and outcomes adjusting for all demographic and health-related covariates. Analysis of covariance results (b) report differences in outcomes across MEDAS quartiles adjusting for all demographic and health-related covariates. | ||||||||||||
(a) Multiple Regression Results | (b) Analysis of Covariance Results | |||||||||||
Outcome | B | 95% CI | β | p | F3,547 | ηp2 | p | Q1: M [95% CI] | Q2: M [95% CI] | Q3: M [95% CI] | Q4: M [95% CI] | |
MSFC | 0.095 | 0.055 | 0.134 | 0.18 | <0.001 | 7.86 | 0.041 | <0.001 | −1.48 [−1.67, −1.30] | −1.15 [−1.30, −1.00] | −0.96 [−1.12, −0.80] | −0.84 [−1.04, −0.64] |
SDMT | 0.869 | 0.458 | 1.279 | 0.17 | <0.001 | 5.44 | 0.029 | 0.001 | 47.9 [46.0, 49.8] | 50.8 [49.2, 52.4] | 52.8 [51.1, 54.4] | 53.1 [51.0, 55.2] |
NHPT | −0.392 | −0.584 | −0.199 | −0.17 | <0.001 | 5.78 | 0.031 | <0.001 | 24.9 [24.0, 25.8] | 23.7 [23.0, 24.5] | 22.8 [22.0, 23.6] | 22.2 [21.2, 23.1] |
T25FW | −0.077 | −0.121 | −0.033 | −0.14 | 0.001 | 5.28 | 0.028 | 0.001 | 5.34 [5.14, 5.55] | 4.95 [4.77, 5.12] | 4.89 [4.71, 5.06] | 4.75 [4.53, 4.97] |
MSISphys | −0.993 | −1.609 | −0.377 | −0.13 | 0.002 | 2.71 | 0.015 | 0.044 | 42.8 [40.0, 45.7] | 39.7 [37.3, 42.1] | 39.3 [36.8, 41.8] | 36.4 [33.3, 39.5] |
FSS | −0.102 | −0.170 | −0.034 | −0.13 | 0.003 | 2.70 | 0.015 | 0.045 | 3.91 [3.60, 4.22] | 3.80 [3.53, 4.06] | 3.61 [3.34, 3.88] | 3.25 [2.91, 3.60] |
MSWS | −1.312 | −2.108 | −0.516 | −0.13 | 0.001 | 3.70 | 0.020 | 0.012 | 45.4 [41.7, 49.1] | 40.0 [36.9, 43.1] | 40.1 [36.9, 43.3] | 35.8 [31.8, 39.9] |
PDQ | −0.056 | −0.091 | −0.022 | −0.13 | 0.001 | 2.27 | 0.012 | 0.079 | 1.55 [1.39, 1.71] | 1.51 [1.38, 1.65] | 1.37 [1.23, 1.51] | 1.26 [1.09, 1.44] |
HADS-D | −0.234 | −0.362 | −0.105 | −0.15 | <0.001 | 4.53 | 0.024 | 0.004 | 5.23 [4.63, 5.82] | 4.39 [3.89, 4.89] | 4.45 [3.94, 4.97] | 3.51 [2.86, 4.16] |
HADS-A | −0.190 | −0.338 | −0.042 | −0.11 | 0.012 | 2.43 | 0.013 | 0.064 | 7.64 [6.95, 8.32] | 7.38 [6.80, 7.95] | 7.11 [6.52, 7.70] | 6.26 [5.51, 7.01] |